Raina Telgemeier uses her signature humor and charm to tell the story of her relationship with her little sister, which unfolds during the course of a road trip from their home in San Francisco to a family reunion in Colorado.

Catrina and her family have moved to the coast of Northern California for the sake of her little sister, Maya, who has cystic fibrosis--and Cat is even less happy about the move when she is told that her new town is inhabited by ghosts, and Maya sets her heart on meeting one.